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zeaxanthin carotenoid xanthophyll cycle plant micro-organism pigment paprika corn saffron goji wolfberries microbes color zea mays yellow xanthophyll non-photochemical quenching photosynthesis carotenoids retina eye supplement biological activity bioactive nutrient prescription drug food additive nutraceutica dietary dye food adjuvants ingredient agent ins number e161h tautomer isomer stereoisomer lutein molecule molecular formula structural structure 3d