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sorbitan anhydrosorbitol dihydroxyethyltetrahydrofurandiol isosorbide surfactant polysorbate emulsifying agent sorbitan ester span nonionic ethoxylated substance matter material compound component stuff reagent functional group precursor synthesis reaction production building block cleansing hydrophilic hydrophobic synthetic detergent zwitterionic surface tension micelle surfaces molecule molecular formula skeletal structural structure 3d chemistry science scientific research organic chemical isomer stereoisomer