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conformer perfluorooctanoic acid pfoa hydrogen oxygen carbon fluorine corrosive irritant health hazard c8hf15o2 molecular formula chemical safety structure model synthetic stable perfluorinated carboxylic fluorosurfactant teflon environment toxicant increased cholesterol chronic kidney disease fluoride toxicology chemistry icon molecule ptfe blood perfluorooctanoate persistent fluorotelomer polytetrafluoroethylene fluoro carcinogen perfluorocaprylic liver environmental