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tanaproget nonsteroidal progestin progesterone receptor pr analog 4-fluoropropyltanaproget radiotracer positron emission tomography radioactive tracer label radiolabeling radiotracing radioisotope feeding hormone hormonal therapy replacement function action endocrine endocrinology level prohormone 3d substance matter material compound component agent stuff reagent functional group precursor synthesis reaction production building block molecule molecular formula skeletal structural structure geometry ball stick atom