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aucubin iridoid glycoside aucuba japonica garryaceae eucommia ulmoides eucommiaceae plantago asiatica major lanceolata plantaginaceae galium aparine rubiaceae carbon tetrachloride alpha-amanitin geranyl pyrophosphate gpp biosynthesis mevalonate pathway terpenoid supplement biological activity bioactive nutrient prescription drug food additive nutraceutica dietary antioxidant anti-cancer anti-aging healthy aging herbal medicine herbal phytochemical phytotherapy plant herb natural herbalism pharmacognosy pharmacopoeia molecule molecular formula structural structure geometry ball stick 3d