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vector icon line sign thermoregulation homeostasis sweat shivering vasodilation vasoconstriction evaporation conduction radiation thermogenesis heatstroke hypothermia mechanoreceptor thermoreceptor endothermic ectothermic thermotaxis piloerection hyperthermia hypoxia thermic effect heat exhaustion cryotherapy hyperthermic homeothermic radiant convective conductive thermoregulatory center sweating rate peripheral acclimation hibernation torpor thermal tolerance comfort cold adaptation energy temperature response body regulation loss gain transfer shock proteins