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probiotic dna cellwall shapes cells geneticmaterial germs gramnegative coccus organisms microflora microorganisms replication extremophiles prokaryotes flagella pathogens methanogens metabolism resistance grampositive bacteria decomposers aerobic spiral symbiotic plasmids thermophiles sell acidophiles nitrogenfixation halophiles microscopic reproduction binaryfission growth nitrogen colonies division pathogenic beneficial anaerobic harmful microbiome unicellular microbes bacillus infection antibiotic ai generated