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primary myelofibrosis hematopoiesis neoplasm myeloproliferative scar tissue acute lymphoblastic leukaemia myeloid amyloid anemia antibody therapy b-cell basophil biological biopsy blood cancer body bone marrow chemotherapy chronic lymphocytic myelogenous deformity disease electrophoresis erythrocytes hematology histology hodgkin lymphoma hypergranular promyelocytic lymphocyte malignant growths mds metastasis monocyte mpns multiple myeloma neutrophil non-hodgkin oncology plasma cell stem t-cell treatment tumor white cells