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abstract age aging anatomical anatomy arthritis background biological biology body bone bones brittle calcium cancellated care cartilage cartoon change close compact condition cut density design diagram disease femur fracture fractures fragility health healthcare healthy hip holes hormone human illustration inflammation inside joint loss macro marrow medical medicine menopause microscopic normal old older organ orthopedic osteoporosis porous problem rheumatism schematic science section simplified skeletal skeleton spine spongy structure system texture thin tissue trauma