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mould fungi madurella illustration microscopic fungus black grain mycetoma maduromycosis infection human extremities nervous system africa asia neglected tropical disease microscope microscopy hyphomycetes grisea mycetomatis mitosporic ascomycota sordariales chronic debilitating deformity leg america india east agar hyphae conidia conidium medicine background structure fungal hand drawn drawing white isolated eumycetoma madura foot eumycotic