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adhesion anatomy bleeding blood bruise bruises bruising capillary care caused cell cells chemokines coagulation cross cytokines damaged dendritic dermatology dermis diagram disease disorders epidermis epithelial fat granulation healing health hematoma hemostasis histamine human illustration infection inflammation inflammatory injury internal leukocyte macrophage macrophages mast maturation medical medicine migration monocyte neutrophil pathogen phagocytosis process regenerate repair response scab science section severe skin splinter structure tissue trauma vessel wound wounded