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Illustration: Cryo-Em Structure Of Human T-Cell Leukemia Virus Type-1 Htlv-1 Intasome

ID 209766007 © Vdvornyk | Megapixl.com

Integration of the reverse-transcribed viral DNA into host chromosomes is a critical step in the life-cycle of retroviruses, including an oncogenic deltaδ-retrovirus human T-cell leukemia virus type-1 HTLV-1. Retroviral integrase forms a higher order nucleoprotein assembly intasome to catalyze the integration reaction. Animated 3D cartoon simulation in three projections, black background.

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Cryo-EM structure of human T-cell leukemia virus type-1 HTLV-1 intasome

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