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Illustration: Chimeric Antigen Receptor Car Therapy: Engineered Receptor Binds To Cd19-Antigen

ID 253411327 © Juangaertner | Megapixl.com

Engineered receptor light blue on the surface of a T-lymphocyte bind specifically to CD19-antigen molecules red on a leukemia cell. This activates a signal cascade in the T-cell leading to the segregation of vesicles that contain perforin and granzyme. The perforins build channels for the granzymes which enter the leukemia cell and activate finally the apoptosis cell death of the cancer cell

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Chimeric antigen receptor CAR therapy: Engineered receptor binds to CD19-antigen

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© Juangaertner | Megapixl.com
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KEYWORDS

antibody antigen artificial bioengineering biomolecule biotechnology cancer car cd19 cell chimeric death enzyme immune immunoreceptor immunotherapy leukemia membrane protein receptor signal specific system tcell therapy tumor

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