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abnormal angiogenesis art artistic arts artwork biological blood body cancer capillary cell cells cellular circulating cluster creation design divide dividing division draft drawing drawn embryonic endothelial expansion factors form formation graphic graphical graphics grow growing growth health healthcare human illustrated illustration malignancies malignant mechanism medical medicine mesoderm metastases metastasis mutate mutations nutrients oxygen pathway physiological piece plan population process processes progressively proteins rapidly secreted secreting shape site splitting spread sprouting therapy transition tumor tumors vasculature vasculogenesis vessel vessels waste work