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abbreviation acronym acth adrenal adrenocorticotropic adrenocorticotropin agent anterior axis banner biological chronically circadian component corticotropin corticotropinreleasing decrease deficient definition diagnostic disease effect gland hormone hypopituitarism hypothalamus important insufficiency level medication phrase pituitary polypeptide precursor produce production response rhythm secreted stress symptom syndrome term tertiary word tropic produced text concept background