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wogonin o-methylated flavone scutellaria baicalensis glycosides wogonosides norwogonin 8-methyl ether oroxylum indicum anxiolytic anticonvulsant positive allosteric modulator benzodiazepine site gabaa receptor supplement biological activity bioactive nutrient prescription drug food additive nutraceutica dietary antioxidant anti-cancer anti-aging healthy aging alternative medicine tcm traditional chinese herbal essential oils herbal phytochemical phytotherapy plant herb natural herbalism pharmacognosy pharmacopoeia parasympathomimetic alkaloid flavonoid molecule molecular formula skeletal structural structure 3d