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tetrachloroethylene tetrachloroethene perchloroethylene pce perc perchloroethene chlorocarbon dry cleaning fabrics dry-cleaning fluid automotive brake cleaner solvent organic nonflammable paint stripper depressant parkinson's disease phosgene bioremediation poison toxicant toxic toxicity toxin toxicology poisoning danger hazard harmful intoxication detoxification carcinogen cancer carcinogenicity carcinogenic carcinogenesis tumor 3d substance matter material compound component reagent functional group precursor synthesis reaction production