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riboflavin 5-phosphate sodium ?106 food additive adjuvants ingredient agent ins number vitamin b2 vitamin milk meat eggs nuts fortified flours green vegetables deficiency microcytic anemia splenomegaly glutathione reductase tissue respiration electron transport system 5-phosphate flavin mononucleotide fmn adenine dinucleotide mitochondrial migraine headache metabolite metabolism biosynthesis mechanism biosynthetic intermediate biogenesis substrate precursor synthesis derivative bioprecursor metabolic molecule molecular formula skeletal structural structure 3d