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quaternium 15 hexamethylenetetramine chloroallyl chloride hexaminium chloride dowicil 75 100 dowco 184 dowicide surfactant preservative cosmetics antimicrobial formaldehyde releaser contact dermatitis allergic reaction sensitive skin synthesis banned patch test allergen carcinogen 3d flammable bleve dangerous cleansing hydrophilic hydrophobic synthetic detergent zwitterionic surface tension micelle surfaces emulsifying toxicant toxic toxicity toxin cancer carcinogenicity carcinogenic carcinogenesis pollutant pollution damage non-biodegradable environment anthropogenic