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illustration heart veins arteries coronary circulatory system ischemia hta hypertension pacemaker arrhythmia tree cholesterol clogged healthy clean stopper thrombopheblitis thrombosis superficial inflammation blood femoral internal external iliac occlusion thrombus section incompetent valves varicose typical channel abnormal dilated deformed valve anatomy venous network skin reticular nodes chronic insufficiency ulcers eczema reverse danger 3d